How many milligrams of synthroid

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How to take Synthroid. Missed dose. Synthroid and withdrawal and dependence. Takeaway and helpful resources. Exposure to air pollutants may amplify risk for depression in healthy individuals. Costs associated with obesity may account for 3. Related Coverage. What to know about thyroid function and hair loss. Medically reviewed by Maria S. Prelipcean, MD. Is there a link between menopause and an underactive thyroid?

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There are currently no generic forms of either drug. Brand-name medications usually cost more than generics. You can view cost estimates for these medications on GoodRx.

Synthroid can interact with several other medications. It can also interact with certain supplements as well as certain foods. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Below are lists of medications that can interact with Synthroid. Before taking Synthroid, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. This is because if taken with Synthroid, your diabetes drugs may not work as well as usual to manage your blood sugar level.

In some cases, your doctor may increase the dosage of your diabetes drugs. Or they may recommend that you take additional diabetes medications. But never change the dose of your diabetes medications on your own. Taking certain heartburn medications with Synthroid may affect how well Synthroid works.

For instance, some heartburn drugs can decrease the level of Synthroid in your body. This is because the heartburn medications change the amount of acid you have in your stomach. And Synthroid needs a certain amount of acid in your stomach in order for it to be properly absorbed. If your Synthroid level is decreased, the drug may not work as well as usual. Other medications used to treat heartburn, such as calcium carbonate Tums , may also interact with Synthroid. But Tums actually binds to Synthroid in your stomach, which stops your body from absorbing Synthroid as well as usual.

To help avoid this interaction, you should take Tums at least 4 hours before or 4 hours after your Synthroid dose. If you are taking any heartburn medications, talk with your doctor about whether the medications are safe to use with Synthroid. If you do take heartburn drugs with Synthroid, your doctor may order blood tests more often than usual to monitor your thyroid health.

In addition to the heartburn medications discussed above, other medications used for digestive issues may also interact with Synthroid. This includes the medications:. These medications may decrease the amount of Synthroid in your body. And this interaction could make Synthroid less effective for you. If you do take simethicone or sucralfate with Synthroid, your doctor may order blood tests more often than usual to monitor your thyroid health.

Some drugs used to treat depression may interact with Synthroid. Certain antidepressants can lower the level of Synthroid in your body, while other antidepressants can raise the level. In some cases, your doctor may recommend that you switch to a different antidepressant. Synthroid and certain antidepressants that increase levels of Synthroid. Tricyclic antidepressants TCAs and tetracyclic antidepressants may interact with Synthroid. If you take these drugs with Synthroid, the levels of both Synthroid and the antidepressant may be increased in your body.

This means you may have an increased risk of side effects from both medications. And keep in mind that side effects of Synthroid can include serious conditions, such as irregular heartbeat. The antidepressant sertraline Zoloft may also interact with Synthroid. However, this drug may decrease the level of Synthroid in your body.

This can make Synthroid less effective for you. Certain medications used to treat high cholesterol may interact with Synthroid. In fact, certain cholesterol medications called bile acid sequestrants can decrease the level of Synthroid in your body.

These cholesterol drugs may do this by lowering the amount of Synthroid that your body absorbs. If you take a bile acid sequestrant, your doctor may recommend that you take Synthroid at least 4 hours before you take the bile acid sequestrant. Doing this helps to lower your risk of this drug interaction. And your doctor may also order blood tests more often than usual to monitor your thyroid health.

Certain medications that affect your electrolyte levels may interact with Synthroid. Examples of these medications include:. These medications may decrease the amount of Synthroid that your body absorbs. This can lower the level of Synthroid in your body, making the drug less effective for you. And your doctor may adjust your dosage of Synthroid needed. Phenobarbital, a drug used to treat seizures , may decrease the level of Synthroid in your body.

This could make Synthroid less effective for you. An antibiotic called rifampin Rimactane may decrease the level of Synthroid in your body. If you take Synthroid with rifampin, your doctor may order blood tests more often than usual to monitor your thyroid health. If taken with certain anticoagulants that affect your vitamin K level, Synthroid may increase the effect of the anticoagulant drug in your body.

Anticoagulants are blood thinners. This means that Synthroid may make certain anticoagulants, such as warfarin Coumadin , work better than they usually do. And this may cause your blood to become too thin, which can lead to serious side effects, such as internal bleeding.

Synthroid may decrease the level of digoxin Lanoxin in your body. Digoxin is used to treat certain heart conditions. With this interaction, digoxin may not work as well as usual. In some cases, your doctor may increase your dosage of digoxin.

Taking certain birth control drugs that contain estrogen may decrease the level of certain hormones in your body. This interaction can affect your level of both Synthroid and the birth control medication.

In some cases, your doctor may adjust your dosage of Synthroid. Or they may recommend that you use a different birth control option. Certain mineral supplements may interact with Synthroid. Certain mineral supplements interact with Synthroid by binding to Synthroid inside your stomach. Doing so will help make sure your dose of Synthroid is absorbed like usual. If you have any questions about taking Synthroid with mineral supplements, talk with your doctor. These foods may interact with the drug and change the level of Synthroid in your body.

Coffee may decrease the amount of Synthroid that your body absorbs. This means that if you drink coffee with your dose of Synthroid, you may not be getting the full amount of Synthroid in your dose.

In this case, Synthroid may not work as well as usual for you. Your doctor may recommend that you take your doses of Synthroid at different times than when you drink coffee. Grapefruit and grapefruit juice may both interact with Synthroid, decreasing the level of Synthroid in your body. If your Synthroid level is decreased, the drug may not work as well as usual for you.

Your doctor may recommend that you take your doses of Synthroid at different times than when you consume grapefruit. Or they may recommend that you avoid the fruit altogether.

Soybeans and soybean flour may bind to Synthroid inside your stomach and stop your body from absorbing the drug properly. If you eat soybeans or soybean flour, your doctor may increase your dosage of Synthroid. Doing this will help to make sure that you have enough of the medication in your system.

Your doctor may also order certain blood tests more often than usual to monitor your thyroid. Synthroid may be affected by cottonseed meal. This product may bind to Synthroid inside your stomach and lower the amount of Synthroid your body absorbs. In this case, you may not have enough Synthroid in your body to treat your condition. If you eat cottonseed meal, your doctor may increase your dosage of Synthroid.

Or they may recommend that you decrease the amount of cottonseed meal in your diet. Your doctor may also check certain blood tests more often than usual to monitor your thyroid. Walnuts can bind to Synthroid inside your stomach and lower the amount of Synthroid that your body absorbs. Or they may recommend that you eat other nuts instead.

If you do eat walnuts, your doctor may order certain blood tests more often than usual to monitor your thyroid. Dietary fiber may bind to Synthroid inside your stomach, which can lower the amount of Synthroid your body absorbs. Dietary fiber is fiber that you consume from eating certain foods.

Your doctor may also recommend that you decrease your fiber intake. And they may order certain blood tests more often than usual to monitor your thyroid. Synthroid may affect certain blood tests, such as those used to check your thyroid hormone levels. In addition, a supplement called biotin may interact with labs that are used to check thyroid hormone levels.

Both of these interactions are described below. Biotin supplements may affect the blood tests used to check thyroid hormone levels. In fact, biotin may cause certain blood tests to show a high level of thyroid hormone in your body.

But this interaction is just between the blood test and the biotin supplement. If you take biotin, your doctor may have you take less of the supplement for a few days before you have labs to check your thyroid.

Or your doctor may recommend that you stop taking the biotin supplement before your labs. This is done to be sure that your levels are within a normal range. But keep in mind that Synthroid is a man-made form of the natural thyroid hormone called T4. This means that if you take the drug before having blood work, your T4 level may be falsely elevated. Before having blood tests to check your thyroid, ask your doctor if you should take your Synthroid doses as usual. Your doctor will recommend when you should take your Synthroid dose in relation to when your labs will be done.

Synthroid comes as tablets that are taken by mouth. Synthroid should be taken once daily on an empty stomach. In some cases, your doctor may discuss with you how to take Synthroid at night. You should take Synthroid on an empty stomach without food. If you do eat something, and you forget to take Synthroid, call your doctor or pharmacist. This length of time may depend on the type of food you ate and whether you took any other medications. You may need to wait 4 hours to take your Synthroid after eating.

If you have questions about when to take Synthroid around meals, talk with your doctor or pharmacist. Yes, you can crush, split, or chew Synthroid tablets. For example, to give the drug to children or infants, Synthroid tablets can be crushed and dissolved in 1 to 2 teaspoons 5 to 10 mL of water. This is because Synthroid should be taken on an empty stomach. Synthroid may also be used off-label for other conditions. Synthroid is approved to treat hypothyroidism. With this condition, you can have symptoms such as tiredness and weight gain.

You may also have muscle weakness and constipation. Thyroid hormones are very important to your health because they regulate your metabolism all of the chemical reactions in your body.

The two main thyroid hormones in your body are called T3 and T4. Reduce or withhold dose for 1 week if cardiac symptoms develop or worsen; restart at lower dose. Myxedema coma: use IV levothyroxine. Adults: Monitor TSH 6—8 weeks after dose change then every 6—12 months when stable. Peds: Monitor TSH and total or free-T4 at 2 and 4 weeks after initiation, 2 weeks after dose change then every 3—12 months thereafter. Correct adrenal insufficiency before initiation. Diabetes; monitor glycemic control.

Increased bone resorption and decreased BMD esp. Use lowest effective dose. Nursing mothers. See full labeling. Absorption reduced by some foods eg, soy flour, cottonseed meal, walnuts, fiber, grapefruit juice , aluminum and magnesium hydroxide, simethicone, proton pump inhibitors, iron, sucralfate; monitor.